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Fujian
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2022-07-14 20:18
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Contact：haiyixing(Mr.)
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Area：Fujian
Address：Fujian
Website：http://www.china-naturebio.com/ http://haiyixing.weijia-group.com/
| Nomenclature |
Chinese name: 糜蛋白酶
US Pharmacopoeia Name: Chymotrypsin powder
CAS Number: 9004-07-3
| Structure |
Chymotrypsin (Chymar) is extractedfrom mammalian pancreas
| General Properties |
Appearance: Fine white to creamy powder
Solubility: Reconstitute in 1mM HCl. Soluble at 10mg/ml in 1mM HCl. 2mM calcium chloride serves as a stabilizer. Store aliquoted solutions at -20°C for up to a week.
| Specification |
Items (Standard: USP 40) |
Specifications |
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Description |
Almost white crystalline powder |
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Diluents |
Maltodextrin |
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Assay |
Chymotrypsin |
≥1000 USP. U. per mg |
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Purity |
≤ 5.0% |
Microbial contamination |
|
TAMC |
NMT 10000 CFU/g |
TYMC |
NMT 100 CFU/g |
E. Coli |
Absence CFU/g |
Salmonellae |
Absence CFU /10g |
| Applications |
*Nutritional formulas (tablets/capsules/powders) as a digestive aid
*Food/Cheese manufacturing
*Hydrolysis of proteins,carbohydrates or fats
*Animal Health formulas as a digestive aid
*Leather hides preparation
*Meat tenderizing formulas
| Packaging |
Net 25kg/fiber drum with inner-LDPE bag
| Shelf life and storage |
24 months(not exceeding 30℃,70% RH), in an airtight container.
| Product Description |
Chymotrypsin 1000 USP is a proteolytic enzyme, found in pancreatic juice, that catalyzes the hydrolysis of proteins into polypeptides and amino acids. CAS：9004-07-3
chymotrypsin 1000 USP is a serine peptidase and has 241 amino acid residues contained in three polypeptide chains (A chain-13 residues, B chain-131 residues, and C chain-97 residues) linked by disulfide bridges. Molecular weight of this enzyme is found to be 25 kDa. Its pI is 8.75. It selectively hydrolyzes peptide bonds on the C-terminal side of tyrosine, phenylalanine, tryptophan, and leucine. Ca2+ activates and stabilizes the enzyme. The enzyme is inhibited by diisopropyl fluorophosphate (DFP), phenylmethanesulfonyl fluoride (PMSF), N-p-tosyl-L-phenylalanine chloromethyl ketone (TPCK), chymostatin, aprotinin, α1-antitrypsin, α2-macroglobulin, 10 mM Cu2+ and Hg2+.
Chymotrypsin 1000 US 1500 USPfrom bovine has been used in a study to inform proteasome inhibition in order to advance anticancer research. α-Chymotrypsin from bovine has also been used in a study that functionalized surface anchored poly(methylhydrosiloxane) thin films on oxidized silicon wafers.
1). For ophthalmology to relax the ciliary ligament, reduce traumatic iridocyclitis; also can be used for cataract extraction, making the crystal easy to remove.
2). For wound healing or post-operative wound healing, anti-inflammatory and prevent local edema, hemorrhage, sprained hematoma, edema after breast surgery, otitis media, rhinitis.
3). For the treatment of chronic bronchitis, bronchiectasis or lung abscess, both purulent and non-purulent sputum can be liquefied and easy to cough up.
4). Treatment of snake bites.
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